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L-saccharopine oxidase

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L-saccharopine oxidase
Identifiers
EC no.1.5.3.18
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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L-saccharopine oxidase (EC 1.5.3.18, FAP2) is an enzyme with systematic name L-saccharopine:oxygen oxidoreductase (L-glutamate forming).[1][2] This enzyme catalyses the following chemical reaction

N6-(L-1,3-dicarboxypropyl)-L-lysine + H2O + O2 (S)-2-amino-6-oxohexanoate + L-glutamate + H2O2

The enzyme is involved in pipecolic acid biosynthesis.

References

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  1. ^ Yoshida N, Akazawa S, Katsuragi T, Tani Y (2004). "Characterization of two fructosyl-amino acid oxidase homologs of Schizosaccharomyces pombe". Journal of Bioscience and Bioengineering. 97 (4): 278–80. doi:10.1016/S1389-1723(04)70204-2. PMID 16233628.
  2. ^ Wickwire BM, Wagner C, Broquist HP (September 1990). "Pipecolic acid biosynthesis in Rhizoctonia leguminicola. II. Saccharopine oxidase: a unique flavin enzyme involved in pipecolic acid biosynthesis". The Journal of Biological Chemistry. 265 (25): 14748–53. PMID 2394693.
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