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The show celebrates its 25th anniversary with a studio audience for the first time during Kimmel's era as host.
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The beloved ABC morning show has been airing pre-recorded interviews and segments for the past week.
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"Oh, you’re standing out in that picture," Barrymore told the comedian.
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Charlie Sheen and Chuck Lorre aren't the only Two and a Half Men alums involved in the new Max comedy.
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"Assuming he’s in a good place, I’m in a good place," Lorre said of Sheen.
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It's a passion project of sorts for comedian Sebastian Maniscalco.
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Don't be afraid of this week's new movies on demand.
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Beloved comedian Sebastian Maniscalco is teaming up with legendary actor Robert De Niro.
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Their public feud led to Sheen being fired from Two And A Half Men in 2011.
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Find out what joke is his best pants-splitter!
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Can you imagine a merch table with CPAP machines, tho?
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The popular stand-up comedian is a natural at hosting a cooking show.
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By our count, 66 comedians released hour-long specials across Netflix, HBO, Comedy Central, Showtime and more. These were the best.
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This "Robert De Niro" guy is going places.
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This year's show features performances from Taylor Swift, Missy Elliott, Miley Cyrus, and more!
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The VMAs will air live Monday, August 26 on MTV.
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Plus Apollo 11, Los Espookys Season Finale, The Wedding Date and more!
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It's one thing to hear Maniscalco relate the foibles of his life to us. It's quite another to watch him do it.
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"Don't do some weird workout that you saw."
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I guess I like a strong female lead, ok?