[CITATION][C] Competitive cooperation of hemagglutinin and neuraminidase during influenza a virus entry. Viruses 11: 458
R Du, Q Cui, L Rong - 2019
[HTML][HTML] Competitive cooperation of hemagglutinin and neuraminidase during influenza A virus entry
R Du, Q Cui, L Rong�- Viruses, 2019 - mdpi.com
The hemagglutinin (HA) and neuraminidase (NA) of influenza A virus possess antagonistic
activities on interaction with sialic acid (SA), which is the receptor for virus attachment. HA
binds SA through its receptor-binding sites, while NA is a receptor-destroying enzyme by
removing SAs. The function of HA during virus entry has been extensively investigated,
however, examination of NA has long been focused to its role in the exit of progeny virus
from infected cells, and the role of NA in the entry process is still under-appreciated. This�…
activities on interaction with sialic acid (SA), which is the receptor for virus attachment. HA
binds SA through its receptor-binding sites, while NA is a receptor-destroying enzyme by
removing SAs. The function of HA during virus entry has been extensively investigated,
however, examination of NA has long been focused to its role in the exit of progeny virus
from infected cells, and the role of NA in the entry process is still under-appreciated. This�…
Showing the best results for this search. See all results